Bromine → 5-Bromo-3,3-dimethylbenzofuran-2(3H)-one

HRID 858591

反応式

HRID 858591 の反応式
[CH3:1][C:2]1([CH3:12])[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]1=[O:11].[Br:13]Br>C(O)(=O)C>[Br:13][C:8]1[CH:9]=[CH:10][C:5]2[O:4][C:3](=[O:11])[C:2]([CH3:12])([CH3:1])[C:6]=2[CH:7]=1

参加物

4

反応物 2

HCID 24408BromineHCID 5956202(3H)-Benzofuranone, 3,3-dimethyl-

生成物 1

HCID 162206345-Bromo-3,3-dimethylbenzofuran-2(3H)-one

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

3,3-Dimethyl-3H-benzofuran-2-one (2.81 g, 17.3 mmol) was added to a solution of Bromine (1.51 mL, 29.5 mmoL) and Acetic acid (35 mL) at room temperature, then stirred overnight. The resulting mixture was stripped of solvent, then distilled under high vacuum. The product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

後処理

  1. distillationdistilled under high vacuum
  2. customThe product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

出典と根拠

ORDレコード
ord-d713a1dfac634009a7cc69c2a7c1e159
出典データセット
uspto-grants-2006_12
特許番号
US07148226B2

関連ノート

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