(4'-Methoxy-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester → Carbamic acid,(3-amino-4'-methoxy[1,1'-biphenyl]-4-yl)-,1,1-dimethylethyl ester

HRID 859302ノート

反応式

HRID 859302 の反応式
[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)=[CH:10][C:9]=1[N+:22]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)=[CH:10][C:9]=1[NH2:22])([CH3:4])([CH3:2])[CH3:3]

参加物

3

反応物 1

HCID 69592776(4'-Methoxy-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

生成物 1

HCID 69592815Carbamic acid,(3-amino-4'-methoxy[1,1'-biphenyl]-4-yl)-,1,1-dimethylethyl ester

試薬・触媒・溶媒 1

HCID 935Nickel触媒

実験手順

Prepared from (4′-methoxy-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example B1) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a white solid (77 mg).

出典と根拠

ORDレコード
ord-4e67f6ddad5343318dc66a6151894ce5
出典データセット
uspto-grants-2006_12
特許番号
US07151098B2

反応ノート

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