Cyclopropaneacetic acid → N-(Cyclopropylacetyl)-L-alanine

HRID 860186

反応式

HRID 860186 の反応式
[CH:1]1([CH2:4][C:5]([OH:7])=O)[CH2:3][CH2:2]1.Cl.C[O:10][C:11](=[O:15])[C@H:12]([CH3:14])[NH2:13]>>[CH:1]1([CH2:4][C:5]([NH:13][C@H:12]([C:11]([OH:15])=[O:10])[CH3:14])=[O:7])[CH2:2][CH2:3]1

参加物

3

反応物 2

HCID 138440Cyclopropaneacetic acidHCID 2733257Alanine methyl ester hydrochloride

生成物 1

HCID 54556694N-(Cyclopropylacetyl)-L-alanine

実験手順

Following General Procedure A above using cyclopropylacetic acid (Aldrich) and L-alanine methyl ester hydrochloride (Sigma), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.15 in 25% ethyl acetate/hexanes) and purification was by flash column chromatography using 25% ethyl acetate/hexanes as the eluant.

後処理

  1. customThe reaction was monitored by tlc on silica gel (Rf=0.15 in 25% ethyl acetate/hexanes) and purification

出典と根拠

ORDレコード
ord-e8ee5bfb1ccd4553b47217c776c9e5be
出典データセット
uspto-grants-2006_12
特許番号
US07153847B2

関連ノート

読み込み中…