化工社化工社 化学情報印刷レポート · 研究参考用
Isobutylamine → 4-Isobutyl-3-nitro quinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isobutylamine | HCID 6558 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 4-Chloro-3-nitroquinoline | HCID 11275808 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 4-Isobutyl-3-nitro quinoline | HCID 22590498 | — |
反応手順
4-chloro-3-nitro-quinoline is reacted with isobutyl amine in the presence of triethylamine (TEA) at between −10 and +15° C. in toluene, while excluding moisture. After washing and phase separation, the organic solution is ready for the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07153967B2 |
| 出典データセット | uspto-grants-2006_12 |
| ORD ID | ord-2a09a96c7904400188fdc1d1d1d2e948 |
| 出典メモ | uspto-grants-2006_12 |