Diazomethane → 2-(3-Nitrobenzoyl)-3-methoxycarbonylpyridine

HRID 861950ノート

反応式

HRID 861950 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:18]=[CH:19][CH:20]=1)[C:7]([C:9]1[C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=[CH:11][N:10]=1)=[O:8])([O-:3])=[O:2].[N+](=[CH2:23])=[N-]>C(Cl)Cl>[N+:1]([C:4]1[CH:5]=[C:6]([CH:18]=[CH:19][CH:20]=1)[C:7]([C:9]1[C:14]([C:15]([O:17][CH3:23])=[O:16])=[CH:13][CH:12]=[CH:11][N:10]=1)=[O:8])([O-:3])=[O:2]

参加物

4

反応物 2

HCID 9550DiazomethaneHCID 197007952-(3-Nitrobenzoyl)-3-carboxypyridine

生成物 1

HCID 197007162-(3-Nitrobenzoyl)-3-methoxycarbonylpyridine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

2-(3-Nitrobenzoyl)-3-carboxypyridine was dissolved in 20 ml of methylene chloride and the solution was cooled in an ice/water bath. Diazomethane (25 ml, 0.33M) was added to the solution and stirred for 2 hours. The solvent was removed and the residue chromatographed (methylene chloride) yielding 0.26 g of 2-(3-nitrobenzoyl)-3-methoxycarbonylpyridine.

後処理

  1. temperaturethe solution was cooled in an ice/water bath
  2. customThe solvent was removed
  3. customthe residue chromatographed (methylene chloride)

出典と根拠

ORDレコード
ord-667a28e15a2c46cdb454835928c70ac3
出典データセット
uspto-grants-1998_02
特許番号
US05716954

反応ノート

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