Methane → HCID 131720463、化合物

HRID 861996ノート

反応式

HRID 861996 の反応式
[CH2:1]([O:3][P:4]([O:20][CH2:21][CH3:22])([C:6]1[N:11]2[CH:12]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:14]=[C:10]2[CH:9]=[CH:8][CH:7]=1)=[O:5])[CH3:2].C.P(CC1C2N(C=C(C(O)=O)N=2)C=CC=1)(O)(O)=O.O1CCOCC1.[Cl:47]Cl>CCOCC>[ClH:47].[CH2:1]([O:3][P:4]([O:20][CH2:21][CH3:22])([C:6]1[N:11]2[CH:12]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:14]=[C:10]2[CH:9]=[CH:8][CH:7]=1)=[O:5])[CH3:2]

参加物

7

反応物 5

HCID 297MethaneHCID 24526ChlorineHCID 312751,4-DioxaneHCID 19701110Ethyl 5-(diethoxyphosphinyl)imidazo[1,2-a]pyridine-2-carboxylateHCID 19701381HCID 19701381、化合物

生成物 1

HCID 131720463HCID 131720463、化合物

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

The product from Example 51 (1.6 g, 4.4 mmol) was dissolved in CH2 Cl2 (30 mL), treated with activated charcoal and filtered. To this filtrate was then added 6N HCl in dioxane (0.9 mL, 4.4 mmol) followed by Et2O (100 mL). The precipitated product was filtered, washed with Et2O, and dried in vacuo.

後処理

  1. filtrationfiltered
  2. filtrationThe precipitated product was filtered
  3. washwashed with Et2O
  4. customdried in vacuo

出典と根拠

ORDレコード
ord-756be3881f944587ac22bb3e422c4239
出典データセット
uspto-grants-1998_02
特許番号
US05716964

反応ノート

読み込み中…