Sulfuric Acid → 4-Methylesculetin

HRID 862015

反応式

HRID 862015 の反応式
S(=O)(=O)(O)O.C([O:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17](=[O:19])[CH3:18])=[CH:12][C:11]=1[O:20]C(=O)C)(=O)C.[C:24](OCC)(=O)[CH3:25]>>[CH3:24][C:25]1[C:14]2[C:13](=[CH:12][C:11]([OH:20])=[C:10]([OH:9])[CH:15]=2)[O:16][C:17](=[O:19])[CH:18]=1

参加物

4

反応物 3

HCID 1118Sulfuric AcidHCID 8857Ethyl AcetateHCID 691691,2,4-Triacetoxybenzene

生成物 1

HCID 53195024-Methylesculetin収率 95%

実験手順

45 ml 75% sulphuric acid is added dropwise to a mixture of 5.8 ml ethyl acetate and 11.4 g 1,2,4-triacetoxy- benzene, heated for 30 min to 80° C., poured onto ice, filtered, the precipitate is washed neutral and dried in a vacuum. 8.2 g of the title compound (95 % of theory) is obtained with a melting point of 270° to 272° C.

後処理

  1. temperatureheated for 30 min to 80° C.
  2. additionpoured onto ice
  3. filtrationfiltered
  4. washthe precipitate is washed neutral
  5. customdried in a vacuum

出典と根拠

ORDレコード
ord-b7718f58bde9494b95ff5117de0e5b01
出典データセット
uspto-grants-1998_02
特許番号
US05716983

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