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HRID 862284作成日:2026年10月26日

2-(3-Methoxyphenyl)-2-propanamine → N-[1-(3-Methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide

https://huagongshe.com/reaction/862284

反応式

関与物質

役割名称HCID仕込み量
反応物2-(3-Methoxyphenyl)-2-propanamineHCID 13911310—
反応物S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylateHCID 15380265—
生成物N-[1-(3-Methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamideHCID 6764684164%

反応手順

Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-(3-methoxyphenyl)-1-methylethylamine (prepared as described in Preparation 10b) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 64%.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05717088
出典データセットuspto-grants-1998_02
ORD IDord-557e9c1ae0394fb9a640d08505ac07a5
出典メモuspto-grants-1998_02