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2-(3-Methoxyphenyl)-2-propanamine → N-[1-(3-Methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(3-Methoxyphenyl)-2-propanamine | HCID 13911310 | — |
| 反応物 | S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylate | HCID 15380265 | — |
| 生成物 | N-[1-(3-Methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide | HCID 67646841 | 64% |
反応手順
Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-(3-methoxyphenyl)-1-methylethylamine (prepared as described in Preparation 10b) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 64%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05717088 |
| 出典データセット | uspto-grants-1998_02 |
| ORD ID | ord-557e9c1ae0394fb9a640d08505ac07a5 |
| 出典メモ | uspto-grants-1998_02 |