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Dicyclohexylcarbodiimide → N-(2-pyridylmethyl)benzhydrylsulphinylacetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 反応物 | 2-Pyridinemethanamine | HCID 19509 | — |
| 反応物 | Modafinil acid | HCID 3085267 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N-(2-pyridylmethyl)benzhydrylsulphinylacetamide | HCID 15225687 | — |
反応手順
To a suspension of 15.44 g (0.06 mol) of benzhydrylsulphinylacetic acid in 90 ml of methylene chloride are added 6.48 g (0.06 mol, i.e. 6.17 ml) of 2-aminomethylpyridine and 12.36 g (0.06 mol) of dicyclohexylcarbodiimide are added to the solution thus obtained. The mixture is heated at reflux for about 3 to 4 hours, then left to cool.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05719168 |
| 出典データセット | uspto-grants-1998_02 |
| ORD ID | ord-6769afe3f93e45529751b5d6b490635d |
| 出典メモ | uspto-grants-1998_02 |