2-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol → 2-Amino-2-(1,2-dihydroxyoctadecyl)-1,3-propanediol

HRID 862850ノート

反応式

HRID 862850 の反応式
[NH2:1][C:2]([CH:7]([OH:26])[CH:8]([OH:25])[CH2:9][CH:10]=[CH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([CH2:5][OH:6])[CH2:3][OH:4]>CO.[C].[Pd]>[NH2:1][C:2]([CH:7]([OH:26])[CH:8]([OH:25])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([CH2:3][OH:4])[CH2:5][OH:6]

参加物

4

反応物 1

HCID 538638012-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol

生成物 1

HCID 218493532-Amino-2-(1,2-dihydroxyoctadecyl)-1,3-propanediol収率 50.2%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 887Methanol溶媒

実験手順

2-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol (68.0 mg) was dissolved in 14 ml of methanol and 6.8 mg of 5% palladium-carbon was added thereto. The catalytic reduction was conducted at ordinary temperature and at atmospheric pressure day and night. After the reaction, the catalyst was filtered off and the filtrate was concentrated under reduced pressure to give 34.3 mg of the subject compound.

後処理

  1. customAfter the reaction
  2. filtrationthe catalyst was filtered off
  3. concentrationthe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-94582ee474eb43a884fdfb9e77a27994
出典データセット
uspto-grants-1998_02
特許番号
US05719176

反応ノート

読み込み中…