HCID 54678585、化合物 → 7,8-Dihydropyrido[1,2-a]indol-9(6H)-one
反応式
[OH:1][C:2]1[C:7]2=[CH:8][C:9]3[C:14]([N:6]2[CH2:5][CH2:4][C:3]=1C(OCC)=O)=[CH:13][CH:12]=[CH:11][CH:10]=3>C(O)C.O.Cl>[CH:10]1[CH:11]=[CH:12][CH:13]=[C:14]2[C:9]=1[CH:8]=[C:7]1[C:2](=[O:1])[CH2:3][CH2:4][CH2:5][N:6]12参加物
5
実験手順
A solution of 1.03 g of ethyl 6,7-dihydro-9-hydroxypyrido[1,2-a]indole-8-carboxylate in 20 ml of ethanol, 10 ml of water and 10 ml of concentrated hydrochloric acid was heated at 80° C. for 3 hours. The solvents were evaporated to give 740 mg of 7,8-dihydropyrido[1,2-a]indol-9(6H)-one of melting point 138°-140° C.
後処理
- customThe solvents were evaporated
出典と根拠
- ORDレコード
- ord-acefca05672f4d9689d62e9a41cede22
- 出典データセット
- uspto-grants-1998_02
- 特許番号
- US05721245
反応ノート
読み込み中…