Phenytoin → 5-Isopropylhydantoin

反応式

N1C2C(=CC=CC=2)C=C1CC1NC(=O)NC1=O.[C:18]1([C:24]2(C3C=CC=CC=3)[NH:28][C:27](=[O:29])[NH:26][C:25]2=[O:30])[CH:23]=CC=C[CH:19]=1.C(N1C(=O)C(C)NC1=O)CCC.C(N1C(=O)C(CC2C=CC=CC=2)NC1=O)CCC.C(N1C(=O)CNC1=O)CCC>>[CH3:19][CH:18]([CH:24]1[NH:28][C:27](=[O:29])[NH:26][C:25]1=[O:30])[CH3:23]

参加物

反応物 5

HCID 1775Phenytoin

HCID 3354773-Butyl-5-methylimidazolidine-2,4-dione

HCID 3591483-Butyl-5-(phenylmethyl)-2,4-imidazolidinedione

HCID 5682353-Butylimidazolidine-2,4-dione

HCID 219723355-(1H-indol-2-ylmethyl)-2,4-imidazolidinedione

生成物 1

HCID 1030335-Isopropylhydantoin

実験手順

5-(1H-indol-2-ylmethyl)-2,4-imidazolidinedione; 5,5-diphenyl-2,4-imidazolidinedione; 3-butyl-5-methyl-2,4-imidazolidinedione; 3-butyl-5-(phenylmethyl)-2,4-imidazolidinedione; 3-butyl-2,4-imidazolidinedione,