関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Traumatic Acid | HCID 5283028 | — |
| 反応物 | (1E)-2-[6-[[amino-[(Z)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine | HCID 5360566 | — |
| 反応物 | Water ethanol | HCID 19096565 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | HCID 178512160 | HCID 178512160 | — |
反応手順
2,28 g of trans-traumatic acid (10 mmol) are suspended in 100 ml of a mixture water/ethanol 2: 1 at 4° C., 5,05 g of chlorhexidine base (10 mmol) are added and the mixture is kept under stirring at 4° C. for hours and then at 25° C. overnight. 200 ml of water are added and the mixture is concentrated under vacuum at the volume of about 100 ml and Finally again cooled to 4° C. The resulting precipitate is recovered by filtration, washed three times using 10 ml of cool water and finally dried under high vacuum.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05567716 |
|---|
| 出典データセット | uspto-grants-1996_10 |
|---|
| ORD ID | ord-0b32a9ea0887407ca1fdee8303d5a98d |
|---|
| 出典メモ | uspto-grants-1996_10 |
|---|
