Cyanoacetic acid → 3-Amino-3,3-diphosphonopropanoic acid
反応式
[C:1]([CH2:3][C:4]([OH:6])=[O:5])#[N:2].[P:7]([OH:10])([OH:9])[OH:8]>CC(C)=O>[NH2:2][C:1]([P:7]([OH:10])([OH:9])=[O:8])([P:7]([OH:10])([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=[O:5]参加物
4
反応条件
- 温度
- 165 °C
実験手順
A mixture of cyanoacetic acid (4.3 g, 0.5 mole), phosphorous acid (8.2 g, 0.1 mole), ISOPAR-M (20 g), and the wetting agents (0.25 g each) was heated at 165° C for 2 hours. The product was worked up with acetone to get yellow crystals of 1-amino-1,1-diphosphono-2-carboxy ethane, m.p. 255° C (decomposition), 55%, associated with traces of impurities.
出典と根拠
- ORDレコード
- ord-c6f4be4f1c3b4c00887c53a220298922
- 出典データセット
- uspto-grants-1978_07
- 特許番号
- US04100167
反応ノート
読み込み中…