Hydrochloric Acid → Adamantane, 1-(2-aminopropyl)-, hydrochloride

HRID 866549ノート

反応式

HRID 866549 の反応式
[C:1]12([CH2:11][CH:12]([NH2:14])[CH3:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[ClH:15]>CCOCC>[ClH:15].[C:1]12([CH2:11][CH:12]([NH2:14])[CH3:13])[CH2:8][CH:7]3[CH2:6][CH:5]([CH2:4][CH:3]([CH2:9]3)[CH2:2]1)[CH2:10]2

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 38375Adamantylamphetamine

生成物 1

HCID 38374Adamantane, 1-(2-aminopropyl)-, hydrochloride

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

β-(1-Adamantyl)-α-methylethylamine (13.3 gm.) was dissolved in 550 ml. anhydrous ether and acidified with HCl gas. The solid was filtered, dried under vacuum at 88°, dissolved in 150 ml. CHCl3, and 850 ml. petroleum ether added to give 15 gm. product, m.p. 295°-7°.

後処理

  1. filtrationThe solid was filtered
  2. customdried under vacuum at 88°
  3. dissolutiondissolved in 150 ml
  4. additionpetroleum ether added
  5. customto give 15 gm

出典と根拠

ORDレコード
ord-b5fb0776596649dca361787739dd370a
出典データセット
uspto-grants-1978_07
特許番号
US04100170

反応ノート

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