Oxalic Acid → 3-(2-Nitrophenoxy)propane-1,2-diol
反応式
[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[O:6][CH2:7][CH:8]1[CH2:10][O:9]1)([O-:3])=[O:2].C(O)(=O)C(O)=[O:17].O1CCOCC1>O>[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[O:6][CH2:7][CH:8]([OH:17])[CH2:10][OH:9])([O-:3])=[O:2]参加物
5
実験手順
To a stirred solution of 38 parts of 2-(2-nitrophenoxymethyl)-oxirane in 10 parts of ethanedioic acid and 300 parts of 1,4-dioxane are added 100 parts of water. The whole is stirred and refluxed for 2 days. The reaction mixture is evaporated and the residue is crystallized from a mixture of 2,2'-oxybispropane and petroleumether. The product is filtered off and recrystallized from 2,2'-oxybispropane, yielding 29.5 parts (13%) of 3-(2-nitrophenoxy)-1,2-propanediol; mp. 96° C..
後処理
- temperaturerefluxed for 2 days
- customThe reaction mixture is evaporated
- customthe residue is crystallized from a mixture of 2,2'-oxybispropane and petroleumether
- filtrationThe product is filtered off
- customrecrystallized from 2,2'-oxybispropane
出典と根拠
- ORDレコード
- ord-459458efce34495c9dfb8732fed96436
- 出典データセット
- uspto-grants-1978_07
- 特許番号
- US04101665
反応ノート
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