関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 3-Chloro-2-methyl-1-propene | HCID 11241 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | Dibenzo-18-crown-6 | HCID 26541 | — |
| 反応物 | 1-(3,3-Dimethylcyclohexyl)ethanone | HCID 91388 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1,1-Dimethylcyclohexane | HCID 11549 | — |
| 生成物 | 1-Acetyl-3,3-dimethyl-1-(2-methyl-2-propenyl)cyclohexane | HCID 20384605 | — |
反応手順
A slurry of potassium hydroxide (84 grams, 1.5 moles), 1-acetyl-3,3-dimethylcyclohexane (156 grams, 1 mole), dibenzo-18-crown-6 (3 grams) having the structure: ##STR24## produced by the Aldrich Chemical Company of Metuchen, New Jersey, and toluene (150 ml) is heated to reflux whereupon the reaction mass thickens. The mass is cooled to 70° C., and methallyl chloride (135 grams, 1.5 moles) is added thereto rendering the reaction mixture more fluid. The reaction mixture is heated at reflux for an additional 9 hours whereupon the mass is cooled, and water is added. The aqueous layer is decanted, and the organic layer is distilled to afford 3,3-dimethylcyclohexane (62 gm) and 1-acetyl-3,3-dimethyl-1-(2-methyl-2-propenyl) cyclohexane (83 gm) (NMR spectrum, FIG. 1; IR spectrum, FIG. 2).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04102928 |
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| 出典データセット | uspto-grants-1978_07 |
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| ORD ID | ord-82fd64f27dd14c20a48c69d2f25da563 |
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| 出典メモ | uspto-grants-1978_07 |
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