化工社化工社 化学情報印刷レポート · 研究参考用
Toluene → 1-(3,3-Dimethylcyclohexyl)-pent-4-en-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | Allyl chloride | HCID 7850 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 1-(3,3-Dimethylcyclohexyl)ethanone | HCID 91388 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1-(3,3-Dimethylcyclohexyl)-pent-4-en-1-one | HCID 6453423 | — |
| 生成物 | 1-[3,3-Dimethyl-1-(prop-2-en-1-yl)cyclohexyl]ethan-1-one | HCID 14817851 | — |
| 生成物 | 5-Dimethyl-2-octanone | HCID 20317600 | — |
反応手順
A slurry of 1-acetyl-3,3-dimethylcyclohexane (156 grams, 1 mole), potassium hydroxide (86 grams, 1.5 moles), and toluene (300 ml) is heated to reflux. Allyl chloride (114 grams, 1.5 moles) is added to the thickened reaction mass whereupon the mass becomes more fluid. The mixture is heated at reflux for 61/2 hours. At the end of this period, the reaction mass is cooled to room temperature, and 500 ml of water is added thereto. The aqueous layer is discarded, and the organic layer is distilled to afford 74 grams of recovered 1-acetyl-3,3-dimethyl hexane, 53 grams of 1-acetyl-3,3-dimethyl-1-(2-propenyl) cyclohexane, and 35 grams of 3,3-dimethyl-1-(4-pentenoyl) cyclohexane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04102928 |
| 出典データセット | uspto-grants-1978_07 |
| ORD ID | ord-1f6a393529744b2383390b63bdc38053 |
| 出典メモ | uspto-grants-1978_07 |