Acetic Acid → 4-[(1E)-3-(Acetyloxy)-1-propen-1-yl]-2-methoxyphenol

HRID 867165ノート

反応式

HRID 867165 の反応式
C([O:4][C:5]1[C:6]([O:14][CH3:15])=[CH:7][C:8]([CH2:11][CH:12]=[CH2:13])=[CH:9][CH:10]=1)(=O)C.[C:16]([OH:19])(=[O:18])[CH3:17]>>[C:16]([O:19][CH2:13]/[CH:12]=[CH:11]/[C:8]1[CH:9]=[CH:10][C:5]([OH:4])=[C:6]([O:14][CH3:15])[CH:7]=1)(=[O:18])[CH3:17]

参加物

3

反応物 2

HCID 176Acetic AcidHCID 7136Eugenyl Acetate

生成物 1

HCID 128354304-[(1E)-3-(Acetyloxy)-1-propen-1-yl]-2-methoxyphenol

実験手順

A mixture of eugenol acetate (16 g,0.0777 mol) and mercuric acetate (44.5 g, 1.4 mol) in 160 ml of acetic acid was refluxed for 20 hr. After filtration, the acetic acid solution was poured into water (150 ml) and extracted with ether (200 ml). The etheral solution was washed successively with water, aqueous NaHCO3, saturated NaCl solution and dried (Na2SO4). The solvent was evaporated to give 18 g of coniferyl acetate. Subsequent reduction of the coniferyl acetate with Red-Al gave coniferyl alcohol.

後処理

  1. temperaturewas refluxed for 20 hr
  2. filtrationAfter filtration
  3. additionthe acetic acid solution was poured into water (150 ml)
  4. extractionextracted with ether (200 ml)
  5. washThe etheral solution was washed successively with water, aqueous NaHCO3, saturated NaCl solution
  6. dry with materialdried (Na2SO4)
  7. customThe solvent was evaporated

出典と根拠

ORDレコード
ord-7444acb56e3146819047587fbf5339b9
出典データセット
uspto-grants-1978_07
特許番号
US04103006

反応ノート

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