4'-Chloroacetyl(acetanilide) → N,N-Dimethyl-N-(p-aminophenacyl)-N-3-aminopropylammonium chloride

HRID 867247

反応式

HRID 867247 の反応式
[CH3:1][N:2]([CH3:9])[CH2:3][CH2:4][CH2:5][NH:6]C=O.C([NH:13][C:14]1[CH:23]=[CH:22][C:17]([C:18](=[O:21])[CH2:19][Cl:20])=[CH:16][CH:15]=1)(=O)C>O>[Cl-:20].[CH3:1][N+:2]([CH3:9])([CH2:19][C:18]([C:17]1[CH:16]=[CH:15][C:14]([NH2:13])=[CH:23][CH:22]=1)=[O:21])[CH2:3][CH2:4][CH2:5][NH2:6]

参加物

4

反応物 2

HCID 88054'-Chloroacetyl(acetanilide)HCID 80020N-(3-(dimethylamino)propyl)formamide

生成物 1

HCID 86735871N,N-Dimethyl-N-(p-aminophenacyl)-N-3-aminopropylammonium chloride

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To a stirred solution of 143.5 parts of N-(3-dimethylaminopropyl)formamide and 700 parts of water is added 249 parts of p-acetamidophenacyl chloride. The mixture is stirred at room temperature for 16 hours and then at 60°-65° C. for 2 hours. Insoluble material is removed by filtration. The filtrate is combined with one-half its volume of concentrated hydrochloric acid (36% by weight) and the resulting solution is heated at the boil for 2 hours. The aqueous solution of N,N-dimethyl-N-(p-aminophenacyl)-N-3-aminopropylammonium chloride is used as such in the preparation of dyes.

後処理

  1. waitat 60°-65° C. for 2 hours
  2. customInsoluble material is removed by filtration
  3. temperaturethe resulting solution is heated at the boil for 2 hours
  4. customsuch in the preparation of dyes

出典と根拠

ORDレコード
ord-60bcf2c87c5d42fc86a76f91d1d450f9
出典データセット
uspto-grants-1978_07
特許番号
US04103092

関連ノート

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