Phosgene → 2-Chloro-3-pyridinesulfonylisocyanate

HRID 867835ノート

反応式

HRID 867835 の反応式
[Cl:1][C:2]1[C:7]([S:8]([NH:11][C:12](=[O:18])NCCCC)(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.C(Cl)(Cl)=O>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[C:7]([S:8]([N:11]=[C:12]=[O:18])(=[O:9])=[O:10])=[CH:6][CH:5]=[CH:4][N:3]=1

参加物

4

反応物 2

HCID 6371PhosgeneHCID 12383441HCID 12383441、化合物

生成物 1

HCID 130384352-Chloro-3-pyridinesulfonylisocyanate

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒

実験手順

To 125 ml of dry xylene was added with stirring 20.7 g of 2-chloro-N-(butylcarbamoyl)-3-pyridinesulfonamide. This solution was heated to reflux, and phosgene added until no further uptake of this gas was observed. It was then cooled, filtered and the solvent was removed in vacuo to yield 2-chloro-3-pyridinesulfonylisocyanate as an oil Bp 108°-110° (0.7 mm Hg). This product showed a sharp absorption peak in the infrared region at 2220 cm-1.

後処理

  1. temperatureThis solution was heated
  2. temperatureto reflux
  3. temperatureIt was then cooled
  4. filtrationfiltered
  5. customthe solvent was removed in vacuo

出典と根拠

ORDレコード
ord-da5795e431994b9e898134c43e4dde68
出典データセット
uspto-grants-1988_10
特許番号
US04776878

反応ノート

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