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2-Pyridineethanamine → 1,8,8-Trimethyl-3-[2-(2-pyridinyl)ethyl]-3-azabicyclo[3.2.1]octane-2,4-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Pyridineethanamine | HCID 75919 | — |
| 反応物 | 1,8,8-Trimethyl-3-oxabicyclo[3.2.1]octane-2,4-dione | HCID 94834 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 1,8,8-Trimethyl-3-[2-(2-pyridinyl)ethyl]-3-azabicyclo[3.2.1]octane-2,4-dione | HCID 14235066 | — |
反応手順
A mixture of (-) camphoric anhydride 5 g (0.029 mol), 2-(2-aminoethyl)pyridine 3.6 (0.03 mol) and 50 ml of pyridine was refluxed overnight. The solvent is removed under reduced pressure and the remaining oil boiled in 20 ml of ethanol and allowed to cool.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04777254 |
| 出典データセット | uspto-grants-1988_10 |
| ORD ID | ord-14d27eb0342e4f14801d1f2da1572273 |
| 出典メモ | uspto-grants-1988_10 |