Acetone → Methyl 2-hydroxy-2-(1-oxo-2-propenylamino)acetate

HRID 868293ノート

反応式

HRID 868293 の反応式
[C:1]([NH2:5])(=[O:4])[CH:2]=[CH2:3].C[C:7](=[O:11])[C:8]([O-:10])=[O:9].[CH3:12]C(C)=O>>[C:1]([NH:5][CH:7]([OH:11])[C:8]([O:10][CH3:12])=[O:9])(=[O:4])[CH:2]=[CH2:3]

参加物

4

反応物 3

HCID 180AcetoneHCID 6579AcrylamideHCID 107735Pyruvate

生成物 1

HCID 157058Methyl 2-hydroxy-2-(1-oxo-2-propenylamino)acetate

実験手順

Acrylamide (141.7 parts), methylglyoxylate (144 parts), acetone (1200 ml) and henothiazine (0.05 parts) were mixed and heated to reflux for 6 hours. After filtration and crystallization 180 parts MAG were received as confirmed by chemical analysis.

後処理

  1. temperatureheated
  2. temperatureto reflux for 6 hours
  3. filtrationAfter filtration and crystallization 180 parts MAG

出典と根拠

ORDレコード
ord-e576c12a9e024748bc4a5f05c26adc17
出典データセット
uspto-grants-1988_10
特許番号
US04778869

反応ノート

読み込み中…