Cyclopentylamine → N-Cyclopropyl-1-ethyl[1,2,4]triazolo[4,3-a]quinoxalin-4-amine

反応式

Cl[C:2]1[C:3]2[N:4]([C:12]([CH2:15][CH3:16])=[N:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH:17]1([NH2:20])[CH2:19][CH2:18]1.ClC1C2N(C(CCC)=NN=2)C2C(N=1)=CC=CC=2.C1(N)CCCC1>>[CH:17]1([NH:20][C:2]2[C:3]3[N:4]([C:12]([CH2:15][CH3:16])=[N:13][N:14]=3)[C:5]3[C:10]([N:11]=2)=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH2:19][CH2:18]1

参加物

反応物 4

HCID 2906Cyclopentylamine

HCID 69828Cyclopropylamine

HCID 133857064-Chloro-1-ethyl[1,2,4]triazolo[4,3-a]quinoxaline

HCID 133857074-Chloro-1-propyl[1,2,4]triazolo[4,3-a]quinoxaline

生成物 1

HCID 14280613N-Cyclopropyl-1-ethyl[1,2,4]triazolo[4,3-a]quinoxalin-4-amine

実験手順

The title compound was prepared essentially as described in Example 4 substituting 4-chloro-1-ethyl[1,2,4]triazolo[4,3-a]quinoxaline and cyclopropyl amine for 4-chloro-1-n-propyl[1,2,4]triazolo[4,3-a]quinoxaline and cyclopentanamine respectively; mp 190°-192° C.

出典と根拠

ORDレコード: ord-fee4324684dd4332ad5414eeeb0f2154
出典データセット: uspto-grants-1988_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04780464

反応ノート

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