Water → 6-Methylbenzofuran

HRID 868612ノート

反応式

HRID 868612 の反応式
S(=O)(=O)(O)O.O[CH:7]1[C:11]2[CH:12]=[CH:13][C:14]([CH3:16])=[CH:15][C:10]=2[O:9][CH2:8]1.O>C1C=CC=CC=1>[CH3:16][C:14]1[CH:13]=[CH:12][C:11]2[CH:7]=[CH:8][O:9][C:10]=2[CH:15]=1

参加物

5

反応物 3

HCID 962Water2 回HCID 1118Sulfuric AcidHCID 13013062HCID 13013062、化合物

生成物 1

HCID 869296-Methylbenzofuran

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

Sulfuric acid (0.2 ml) and 10.0 g of 3-hydroxy-6-methyl-2,3-dihydrobenzofuran were dissolved in 200 ml of benzene and heated at reflux with the azeotropic removal of water. After 3 hours, the reaction mixture was added to water (500 ml) and extracted with ether. The combined ether extracts were washed with water and saturated aqueous sodium bicarbonate, dried with sodium sulfate and the solvent evaporated to give 6-methylbenzofuran.

後処理

  1. temperatureheated
  2. extractionextracted with ether
  3. washThe combined ether extracts were washed with water and saturated aqueous sodium bicarbonate
  4. dry with materialdried with sodium sulfate
  5. customthe solvent evaporated

出典と根拠

ORDレコード
ord-aa59cb39a31b47429db72de6c2e5170b
出典データセット
uspto-grants-1988_10
特許番号
US04780480

反応ノート

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