2-(4-Methylmorpholin-2-yl)ethan-1-ol → HCID 86723163、化合物
反応式
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][N:6]=[C:5]2[I:11].[CH3:12][N:13]1[CH2:18][CH2:17][O:16][CH:15]([CH2:19][CH2:20]O)[CH2:14]1>>[I:11][C:5]1[C:4]2[C:8](=[CH:9][CH:10]=[C:2]([F:1])[CH:3]=2)[N:7]([CH2:20][CH2:19][CH:15]2[O:16][CH2:17][CH2:18][N:13]([CH3:12])[CH2:14]2)[N:6]=1参加物
3
実験手順
The title compound was prepared from 5-fluoro-3-iodo-indazole and 2-(4-methylmorpholin-2-yl)ethanol in 80% yield according to the general procedure for Preparation 31A. The minor isomer was not isolated or characterized.
後処理
- customThe minor isomer was not isolated
出典と根拠
- ORDレコード
- ord-ca17bff58f4040f4894acbdf13447641
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08969343B2
反応ノート
読み込み中…