Hydrochloric Acid → HCID 66642852、化合物
反応式
[NH2:1][CH:2]1[CH2:7][CH2:6][C:5]([NH:9]C(=O)OC(C)(C)C)([CH3:8])[CH2:4][CH2:3]1.C(O)C.[ClH:20]>C(OCC)(=O)C>[ClH:20].[ClH:20].[CH3:8][C:5]1([NH2:9])[CH2:6][CH2:7][CH:2]([NH2:1])[CH2:3][CH2:4]1参加物
5
実験手順
To a mixture of tert-butyl (4-amino-1-methylcyclohexyl)carbamate (Preparation Example 399) (3.73 g) and ethanol (30 mL), 4M hydrogen chloride in ethyl acetate (30 mL) was added under ice cooling and stirred at room temperature for 20 hours. The precipitated solid was collected by filtration and washed with ethyl acetate to give 1-methylcyclohexane-1,4-diamine dihydrochloride (2.10 g) as a white solid.
後処理
- additionwas added under ice cooling
- filtrationThe precipitated solid was collected by filtration
- washwashed with ethyl acetate
出典と根拠
- ORDレコード
- ord-a3defbda903c4b33adc2cbe920d52327
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08969336B2
反応ノート
読み込み中…