3-Fluorobenzyl bromide → 6-bromo-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
反応式
[Br:1][C:2]1[N:7]=[C:6]2[NH:8][CH:9]=[C:10]([C:11]#[N:12])[C:5]2=[CH:4][CH:3]=1.Br[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([F:21])[CH:16]=1>>[Br:1][C:2]1[N:7]=[C:6]2[N:8]([CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([F:21])[CH:16]=3)[CH:9]=[C:10]([C:11]#[N:12])[C:5]2=[CH:4][CH:3]=1参加物
3
実験手順
The title compound was prepared as described in Example 28A using 6-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile in place of 6-bromo-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile and using 1-(bromomethyl)-3-fluorobenzene in place of 4-(bromomethyl)tetrahydro-2H-pyran.
出典と根拠
- ORDレコード
- ord-f83eb6eb411b4d3d845b5a8b9df60c5b
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08969375B2
反応ノート
読み込み中…