4-Iodo-1-methyl-1H-pyrazole-5-carboxylic acid → 4-(6-cyanopyridin-2-yl)-1-methyl-1H-pyrazole-5-carboxylic acid
反応式
Br[C:2]1[N:7]=[C:6]([C:8]#[N:9])[CH:5]=[CH:4][CH:3]=1.I[C:11]1[CH:12]=[N:13][N:14]([CH3:19])[C:15]=1[C:16]([OH:18])=[O:17]>>[C:8]([C:6]1[N:7]=[C:2]([C:11]2[CH:12]=[N:13][N:14]([CH3:19])[C:15]=2[C:16]([OH:18])=[O:17])[CH:3]=[CH:4][CH:5]=1)#[N:9]参加物
3
実験手順
Using 6-bromopicolinonitrile (0.73 g) and 4-iodo-1-methyl-1H-pyrazole-5-carboxylic acid (1 g), the title compound (4.7 mg) was obtained in the form of a colorless solid by the same method as that of (Example 3.22) <Step 1> or a method equivalent thereto.
出典と根拠
- ORDレコード
- ord-db62c6dc65dc4055b9f9ca1ebb41ec75
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08980888B2
反応ノート
読み込み中…