1,4-Dioxane hydrochloride → 3-(1,3-Dioxolan-2-yl)propyl piperidine-4-carboxylate hydrochloride
反応式
[ClH:1].O1CCOCC1.[N:8]1(C(OC(C)(C)C)=O)[CH2:13][CH2:12][CH:11]([C:14]([O:16][CH2:17][CH2:18][CH2:19][CH:20]2[O:24][CH2:23][CH2:22][O:21]2)=[O:15])[CH2:10][CH2:9]1>>[ClH:1].[NH:8]1[CH2:13][CH2:12][CH:11]([C:14]([O:16][CH2:17][CH2:18][CH2:19][CH:20]2[O:21][CH2:22][CH2:23][O:24]2)=[O:15])[CH2:10][CH2:9]1参加物
3
実験手順
HCl-dioxane (4 M, 5 mL, 20 mmol) was added to 4-(3-(1,3-dioxolan-2-yl)propyl) 1-tert-butyl piperidine-1,4-dicarboxylate (0.71 g, 2.07 mmol) and the reaction mixture was stirred at RT for 1.5 hours. The solvent was evaporated at reduced pressure. The crude material was used directly without purification.
後処理
- customThe solvent was evaporated at reduced pressure
- customThe crude material was used directly without purification
出典と根拠
- ORDレコード
- ord-4c82da05561c40a7bd066f923e983a6d
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08980913B2
反応ノート
読み込み中…