化工社化工社 化学情報印刷レポート · 研究参考用
Benzene → Methyl 2-nitrobenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzene | HCID 241 | — |
| 反応物 | 2-Nitrobenzoic acid | HCID 11087 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 生成物 | Methyl 2-nitrobenzoate | HCID 69072 | — |
反応手順
A solution of 6-nitro-benzoic acid in benzene was treated with thionyl chloride (2.5 eq) and stirred at reflux for 8 h. After evaporation, the residue was dissolved in chloroform and then treated with methanol. After stirring at reflux for 3 h, the mixture was evaporated to afford compound 3.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08980901B2 |
| 出典データセット | uspto-grants-2015_03 |
| ORD ID | ord-3ab26dc5f94c470a80020d25845e6083 |
| 出典メモ | uspto-grants-2015_03 |