Ethylene → HCID 178476818、化合物

HRID 875275

反応式

HRID 875275 の反応式
C[P:2]([OH:11])([CH2:4][CH2:5][C@H:6](N)C(O)=O)=[O:3].P(Cl)(Cl)Cl.[Cl-:16].[Cl-].[Cl-].[Cl-].[Al+3].[CH2:21]=[CH2:22]>C(O)C>[Cl:16][CH2:6][CH2:5][CH2:4][PH:2](=[O:3])[O:11][CH2:21][CH3:22]

参加物

6

反応物 4

HCID 6325EthyleneHCID 24387Phosphorus trichlorideHCID 91619PhosphinothricinHCID 25114082Aluminum tetrachloride

生成物 1

HCID 178476818HCID 178476818、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Another process of producing phosphinothricin generally comprises converting phosphorus trichloride to an adduct of methylphosphonous trichloride and aluminum tetrachloride (i.e., CH3PCl3.AlCl4). The adduct is reacted with ethylene to form an intermediate adduct, which is then reacted with ethanol to form ethyl 1-(2-chloroethyl)-methylphosphinate. This compound is reacted with potassium hydroxide and ethanol to prepare an ethyl vinylphosphinate precursor. The ethyl vinylphosphinate precursor is subjected to hydroformylation-aminocarbonylation, followed by hydrolysis of the hydroformylation-aminocarbonylation product in the presence of hydrochloric acid to produce phosphinothricin.

後処理

  1. customto form an intermediate adduct, which

出典と根拠

ORDレコード
ord-402523d6d8d74830b45d44bbad92c16d
出典データセット
uspto-grants-2015_03
特許番号
US08981142B2

関連ノート

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