化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → Quinoline-6-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | Quinoline-6-carbonyl chloride | HCID 12391963 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | Quinoline-6-carboxamide | HCID 11052097 | — |
反応手順
To a solution of quinoline-6-carbonyl chloride (0-2) (2.2 g, 10.5 mmol) in THF (100 mL) was added ammonia (5 mL) at 0° C. The mixture was stirred at room temperature for 1 h, then concentrated and washed with water (15 mL) to afford the title compound (1.5 g). MS (m/z): 173 (M+1)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08987269B2 |
| 出典データセット | uspto-grants-2015_03 |
| ORD ID | ord-87238a64770048ebb9f0b78f6339b255 |
| 出典メモ | uspto-grants-2015_03 |