Ammonia → HCID 23371316、化合物
反応式
[NH2:1][C:2]1[C:3]([SH:9])=[N:4][C:5]([Cl:8])=[CH:6][CH:7]=1.N.[CH:11](O)=O>>[Cl:8][C:5]1[N:4]=[C:3]2[S:9][CH:11]=[N:1][C:2]2=[CH:7][CH:6]=1参加物
4
実験手順
3-Amino-6-chloropyridine-2-thiol (Q-3) (16.4 g, 103 mmol) in formic acid (80 mL) was refluxed at 110° C. for 2 h. The reaction mixture was cooled and neutralized with concentrated ammonia to pH 7. A precipitate was collected by filtration as the title compound (14.5 g). MS (m/z): 171 (M+1)+.
後処理
- temperatureThe reaction mixture was cooled
- filtrationA precipitate was collected by filtration as the title compound (14.5 g)
出典と根拠
- ORDレコード
- ord-d2d324eec49e4a3ba1c7a992cb56d34e
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08987269B2
反応ノート
読み込み中…