Imidazo[1,2-b]pyridazin-6-ylmethanol → Imidazo[1,2-b]pyridazin-6-ylmethanamine

HRID 876819

反応式

HRID 876819 の反応式
[N:1]1[CH:2]=[CH:3][N:4]2[C:9]=1[CH:8]=[CH:7][C:6]([CH2:10]O)=[N:5]2.Cl.S1C2C=C[N:18]=CC=2C=C1CN>>[N:1]1[CH:2]=[CH:3][N:4]2[C:9]=1[CH:8]=[CH:7][C:6]([CH2:10][NH2:18])=[N:5]2

参加物

3

反応物 2

HCID 59580099Imidazo[1,2-b]pyridazin-6-ylmethanolHCID 67306703Thieno[3,2-c]pyridin-2-ylmethanamine hydrochloride

生成物 1

HCID 68285393Imidazo[1,2-b]pyridazin-6-ylmethanamine

実験手順

Intermediate 1 was prepared from imidazo[1,2-b]pyridazin-6-ylmethanol (1-4) following the procedures similar to procedure of intermediate D from D-3. MS (m/z): 149 (M+1)+

出典と根拠

ORDレコード
ord-93086784734a4a1e9102864e6c76490e
出典データセット
uspto-grants-2015_03
特許番号
US08987269B2

関連ノート

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