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Diethyl Ether → HCID 46261794、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 3-Methoxyaniline | HCID 10824 | — |
| 反応物 | 4,6-dichloro-1-methyl-1H-pyrazolo(3,4-d)pyrimidine | HCID 222247 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 46261794 | HCID 46261794 | — |
反応手順
m-Anisidine (1.1 eq) was added to a solution of 4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 5 (1 eq.) and triethylamine (NEt3, 1.5 eq) in ethanol. The mixture was stirred at room temperature for 2 hr and then ether was added. The solid was filtered off and the filtrate concentrated in vacuo to give 6-chloro-N-(3-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 6.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08987280B2 |
| 出典データセット | uspto-grants-2015_03 |
| ORD ID | ord-80e6685e623640debceec97824a5680b |
| 出典メモ | uspto-grants-2015_03 |