4-Iodopyridin-3-amine → 4-iodo-N-methylpyridin-3-amine

HRID 878013ノート

反応式

HRID 878013 の反応式
[CH3:1][N:2]([C:19]1[CH:20]=[N:21][CH:22]=[CH:23][C:24]=1N1CCCCC1C)C(=O)C1C=C(C(F)(F)F)C=C(C(F)(F)F)C=1.[I:32]C1C=CN=CC=1N>>[I:32][C:24]1[CH:23]=[CH:22][N:21]=[CH:20][C:19]=1[NH:2][CH3:1]

参加物

3

反応物 2

HCID 8191324-Iodopyridin-3-amineHCID 86670691N-Methyl-N-(2-methyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-yl)-3,5-bis-trifluoromethyl-benzamide

生成物 1

HCID 706632374-iodo-N-methylpyridin-3-amine

実験手順

The title compound was prepared in analogy to example 25, intermediate b, from 4-iodo-pyridin-3-ylamine. Brown oil (22%) which was pure enough to be used in the next step.

出典と根拠

ORDレコード
ord-b365e2b785a843f7861cf0ff5f6e33ba
出典データセット
uspto-grants-2015_03
特許番号
US08987307B2

反応ノート

読み込み中…