3-Fluoropyridine-4-boronic acid → (3'-Fluoro-[4,4]bipyridinyl-3-yl)-methyl-amine
反応式
C[N:2]([C:19]1[CH:20]=[N:21][CH:22]=[CH:23][C:24]=1N1CCCCC1C)[C:3](=O)C1C=C(C(F)(F)F)C=C(C(F)(F)F)C=1.[F:32][C:33]1[CH:34]=[N:35][CH:36]=[CH:37][C:38]=1B(O)O>>[F:32][C:33]1[CH:34]=[N:35][CH:36]=[CH:37][C:38]=1[C:24]1[CH:23]=[CH:22][N:21]=[CH:20][C:19]=1[NH:2][CH3:3]参加物
3
実験手順
The title compound was prepared in analogy to example 69, intermediate, from (4-bromo-pyridin-3-yl)-methyl-amine (example 25, intermediate b) and 3-fluoropyridine-4-boronic acid (CAS RN 458532-97-3). Brown solid (92%). MS (ESI): m/z=204.2 [M+H]+.
出典と根拠
- ORDレコード
- ord-68cdb44f69aa4f13aa67e5b719ea6945
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08987307B2
反応ノート
読み込み中…