6-Chloropyridine-2-boronic acid → (6-Chloro-[2,4]bipyridinyl-3'-yl)-methyl-amine
反応式
C[N:2]([C:19]1[CH:20]=[N:21][CH:22]=[CH:23][C:24]=1N1CCCCC1C)[C:3](=O)C1C=C(C(F)(F)F)C=C(C(F)(F)F)C=1.[Cl:32][C:33]1[N:38]=[C:37](B(O)O)[CH:36]=[CH:35][CH:34]=1>>[Cl:32][C:33]1[N:38]=[C:37]([C:24]2[CH:23]=[CH:22][N:21]=[CH:20][C:19]=2[NH:2][CH3:3])[CH:36]=[CH:35][CH:34]=1参加物
3
実験手順
The title compound was prepared in analogy to example 68, intermediate, from (4-bromo-pyridin-3-yl)-methyl-amine (example 25, intermediate b) and 6-chloropyridine-2-boronic acid (CAS RN 652148-90-8). Brown sticky solid (90%). MS (ESI): m/z=220.0 [M+H]+.
出典と根拠
- ORDレコード
- ord-1fd3010b0e064f808f25931aa7af71d4
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08987307B2
反応ノート
読み込み中…