1-Butanol → Butyl ethyl(2-hydroxyethyl)phosphinate
反応式
[CH2:1]([P:3]([CH2:6][CH2:7][OH:8])(=[O:5])[OH:4])[CH3:2].[CH2:9](O)[CH2:10][CH2:11][CH3:12].O>C1(C)C=CC=CC=1>[CH2:1]([P:3]([CH2:6][CH2:7][OH:8])(=[O:4])[O:5][CH2:9][CH2:10][CH2:11][CH3:12])[CH3:2]参加物
5
実験手順
414 g (3 mol) of ethyl(2-hydroxyethyl)phosphinic acid (produced as in Example 8) are at 85° C. dissolved in 400 ml of toluene and admixed with 888 g (12 mol) of butanol. At a reaction temperature of about 100° C., the water formed is removed by azeotropic distillation to leave 500 g (86% of theory) of butyl ethyl(2-hydroxyethyl)phosphinate.
後処理
- customare at 85° C.
- customis removed by azeotropic distillation
出典と根拠
- ORDレコード
- ord-748250f50db64502a1985fc3cb67ea96
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08987490B2
反応ノート
読み込み中…