(3-Chloropropyl)benzene → 2-(1-benzyl-1H-indole-6-yl)acetic acid

HRID 878975

反応式

HRID 878975 の反応式
[C:1]1([CH2:7][CH2:8][CH2:9]Cl)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:11]([N:18]1[C:26]2[C:21](=[CH:22][CH:23]=[C:24]([CH2:27][C:28]([OH:30])=[O:29])[CH:25]=2)[CH:20]=[CH:19]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[C:1]1([CH2:7][CH2:8][CH2:9][N:18]2[C:26]3[C:21](=[CH:22][CH:23]=[C:24]([CH2:27][C:28]([OH:30])=[O:29])[CH:25]=3)[CH:20]=[CH:19]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:11]([N:18]1[C:26]2[C:21](=[CH:22][CH:23]=[C:24]([CH2:27][C:28]([OH:30])=[O:29])[CH:25]=2)[CH:20]=[CH:19]1)[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

参加物

4

反応物 2

HCID 7706(3-Chloropropyl)benzeneHCID 544889242-(1-benzyl-1H-indole-6-yl)acetic acid

生成物 2

HCID 544889242-(1-benzyl-1H-indole-6-yl)acetic acidHCID 681844222-[1-(3-phenylpropyl)-1H-indole-6-yl]acetic acid

実験手順

The titled compound (44 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 3-phenylpropyl chloride according to the method of the process (7) of Example 4.

出典と根拠

ORDレコード
ord-9ed45e290ca748f3840b42a3ab38ff99
出典データセット
uspto-grants-2015_03
特許番号
US08987473B2

関連ノート

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