Glutathione → S-Nitrosoglutathione

関与物質

反応手順

Briefly, to a stirred ice-cold solution of glutathione (GSH) (154 mg, 0.5 mmol) in 5 ml of 0.2 N HCl was added a portion of NaNO2 (35 mg, 0.5 mmol). This reaction gives GSNO in a high yield of more than 80%. The final red solution was protected from light with aluminum foil and stable in the dark, which allow it to be used directly after synthesis without purification.

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