化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 3-Fluoro-4-nitrobenzoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Fluoro-4-nitrobenzoic acid | HCID 230653 | — |
| 生成物 | 3-Fluoro-4-nitrobenzoyl chloride | HCID 2774656 | 99% |
反応手順
A stirred solution of 3-fluoro-4-nitro-benzoic acid (1.65 g, 8.91 mmol) in thionyl chloride (10 mL) was heated at reflux for 2 h. Excess thionyl chloride was evaporated in vacuo and the residue azeotroped with toluene to afford 3-fluoro-4-nitro-benzoyl chloride (1.7 g, 99%) as a brown oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08993574B2 |
| 出典データセット | uspto-grants-2015_03 |
| ORD ID | ord-8da9e7ed9518459a824ff103d4a188b8 |
| 出典メモ | uspto-grants-2015_03 |