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HRID 881296作成日：2026年10月27日

N,N-dimethyl-2-(piperazin-1-yl)acetamide → 2-[4-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-N,N-dimethyl-acetamide

https://huagongshe.com/reaction/881296

反応式

関与物質

役割名称HCID仕込み量
反応物N,N-dimethyl-2-(piperazin-1-yl)acetamideHCID 2758642—
反応物2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehydeHCID 45789985—
生成物2-[4-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-N,N-dimethyl-acetamideHCID 57493970—

反応手順

Reaction between 2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine-6-carbaldehyde 10 (Example 3) and N,N-dimethyl-2-piperazin-1-yl-acetamide using General Procedure B-3 yielded 2-[4-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-N,N-dimethyl-acetamide.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08993563B2
出典データセットuspto-grants-2015_03
ORD IDord-71e17f0ade914eedb2f927607307d8cf
出典メモuspto-grants-2015_03