Ethyl 2-(4-bromophenyl)-2-methylpropanoate → 2-(1-Benzothiophen-3-yl)-2-methylpropanoic acid

反応式

[S:1]1[CH:5]=[C:4]([C:6]([CH3:12])([CH3:11])[C:7]([O:9]C)=[O:8])[C:3]2[CH:13]=[CH:14][CH:15]=[CH:16][C:2]1=2.BrC1C=CC(C(C)(C)C(OCC)=O)=CC=1>>[S:1]1[CH:5]=[C:4]([C:6]([CH3:12])([CH3:11])[C:7]([OH:9])=[O:8])[C:3]2[CH:13]=[CH:14][CH:15]=[CH:16][C:2]1=2

参加物

反応物 2

HCID 11277257Ethyl 2-(4-bromophenyl)-2-methylpropanoate

HCID 21099806Methyl 2-(benzo[b]thiophen-3-yl)-2-methylpropanoate

生成物 1

HCID 210997132-(1-Benzothiophen-3-yl)-2-methylpropanoic acid

実験手順

The title compound was prepared according to the method of Example 22B substituting the product of Example 49B for the product of Example 22A.

出典と根拠

ORDレコード: ord-99557d634f7f49dab28e936e380d89d8
出典データセット: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08993632B2

反応ノート

読み込み中…