Potassium Hydroxide → HCID 16679760、化合物
反応式
[C:1]([S:5][CH2:6][C:7]1([CH3:14])[NH:11][C:10](=[O:12])[NH:9][C:8]1=[O:13])([CH3:4])([CH3:3])[CH3:2].[OH-:15].[K+]>C1(C)C=CC=CC=1>[C:10]([NH:11][C@:7]([CH3:14])([C:8]([OH:15])=[O:13])[CH2:6][S:5][C:1]([CH3:4])([CH3:3])[CH3:2])(=[O:12])[NH2:9]参加物
4
反応条件
- 温度
- 95 °C
実験手順
First, 5-tert-butylthiomethyl-5-methylhydantoin (5 g, 23 mmol) was mixed with a 65% aqueous potassium hydroxide solution (4.4 g) and toluene (5 ml), and the mixture was heated to 95° C. and stirred for 27 hours. The HPLC analysis of the reaction solution showed the production of the title compound in a reaction yield of 88%.
出典と根拠
- ORDレコード
- ord-69ea7bc27a584fd992b1deb1f60f8f53
- 出典データセット
- uspto-grants-2015_03
- 特許番号
- US08993800B2
反応ノート
読み込み中…