2-Thiopheneglyoxylic acid → 6-hydroxy-3-thiophen-2-yl-1H-quinoxalin-2-one
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[CH:6][C:7]=1[NH2:8].[S:10]1[CH:14]=[CH:13][CH:12]=[C:11]1[C:15](=O)[C:16](O)=[O:17]>>[OH:9][C:4]1[CH:3]=[C:2]2[C:7](=[CH:6][CH:5]=1)[NH:8][C:16](=[O:17])[C:15]([C:11]1[S:10][CH:14]=[CH:13][CH:12]=1)=[N:1]2参加物
3
実験手順
The quinoxalin-2-one of the present example is prepared with 3,4-diaminophenol (which is prepared by treating 3,4-dinitrophenol with H2NNH2.H2O, Pd/C refluxed in MeOH), and (thiophen-2-yl)oxo-acetic acid via the method described in Example 12 to afford 6-hydroxy-3-thiophen-2-yl-1H-quinoxalin-2-one.
出典と根拠
- ORDレコード
- ord-86b6c3f40aed481788cec6f62bb8d5ce
- 出典データセット
- uspto-grants-2012_08
- 特許番号
- US08236807B2
反応ノート
読み込み中…