関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | L-Cysteine, methyl ester, hydrochloride | HCID 2733208 | — |
| 反応物 | 8-Bromo-3-methyl-7-(3-methylbut-2-enyl)-1-(2-oxo-2-phenylethyl)-3,7-dihydropurine-2,6-dione | HCID 24750161 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | HCID 178446233 | HCID 178446233 | — |
反応手順
50 mg of 8-bromo-3-methyl-7-(3-methylbut-2-enyl)-1-(2-oxo-2-phenylethyl) -3,7-dihydropurine-2,6-dione were dissolved in 1 ml of dimethylformamide and, after addition of 24 mg of L-cysteine methyl ester hydrochloride and 37 mg of potassium carbonate, the mixture was heated with stirring at 90° C. for 1 hour. After cooling to room temperature, 10 ml of water were added, and the mixture was made weakly acidic with glacial acetic acid. A precipitate separated out on stirring and was filtered off and dried in a vacuum.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08236810B2 |
|---|
| 出典データセット | uspto-grants-2012_08 |
|---|
| ORD ID | ord-9d0c5bf723fb46f7bf841c35f2ce46e4 |
|---|
| 出典メモ | uspto-grants-2012_08 |
|---|
