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3-(1-Ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-4-trifluoromethoxy-benzaldehyde → 5-[3-(1-Ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-4-trifluoromethoxy-phenyl]-penta-2,4-dienoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(1-Ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-4-trifluoromethoxy-benzaldehyde | HCID 11223449 | — |
| 反応物 | (E)-2,3-diethyl-4-phosphonohex-2-enoate | HCID 86585716 | — |
| 生成物 | 5-[3-(1-Ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-4-trifluoromethoxy-phenyl]-penta-2,4-dienoic acid | HCID 76696833 | — |
反応手順
Compound 24 was prepared from Compound 2A using procedures similar to those described for Example 20B and 20C, except using triethyl-4-phosphonocrotonate in step 20B. MS (electrospray): mass calculated for C26H26F3NO4, 473.18; m/z found 474.2 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08236819B2 |
| 出典データセット | uspto-grants-2012_08 |
| ORD ID | ord-612b86602d6c47ca96baabe3f3040e1f |
| 出典メモ | uspto-grants-2012_08 |