1,4-Dioxane → (3-Chloro-phenyl)-{4-[2-(2-methoxy-1-methyl-ethylamino)-pyridin-4-yl]-pyrimidin-2-yl}-amine

反応式

[Cl:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[n:10][cH:11][cH:12][c:13](-[c:15]3[cH:16][c:17]([Cl:21])[n:18][cH:19][cH:20]3)[n:14]2)[cH:5][cH:6][cH:7]1.[NH2:22][CH:23]([CH2:24][O:25][CH3:26])[CH3:27].[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[n:10][cH:11][cH:12][c:13](-[c:15]3[cH:16][c:17]([NH:22][CH:23]([CH2:24][O:25][CH3:26])[CH3:27])[n:18][cH:19][cH:20]3)[n:14]2)[cH:5][cH:6][cH:7]1

参加物

反応物 3

HCID 312751,4-Dioxane

HCID 123458Methoxyisopropylamine

HCID 9905031N-(3-chlorophenyl)-4-(2-chloropyridin-4-yl)pyrimidin-2-amine

生成物 1

HCID 69666599(3-Chloro-phenyl)-{4-[2-(2-methoxy-1-methyl-ethylamino)-pyridin-4-yl]-pyrimidin-2-yl}-amine

出典と根拠

ORDレコード: ord-677ef650d8984cdc901532f2aa70af9b
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…